Transbronchial cryobiopsy for diffuse parenchymal lung disease: 30- and 90-day mortality

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Transbronchial cryobiopsy in diffuse parenchymal lung disease

The evaluation of patients with diffuse parenchymal lung diseases (DPLD), particularly the idiopathic interstitial pneumonias (IIP), often requires a multidisciplinary team approach. A surgical lung biopsy may be necessary for a confident diagnosis, particularly in patients with atypical clinical/radiological presentations.1 However, surgical lung biopsies carry a risk of serious complications,...

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Learning curve for transbronchial lung cryobiopsy in diffuse lung disease.

INTRODUCTION Transbronchial lung cryobiopsy (TBLC) is increasingly used in the diagnosis of diffuse lung disease (DLD), but no data have yet been published on the learning curve associated with this technique. AIM To evaluate diagnostic yield, lung tissue sample length and area, and procedure-related complications in a cohort of TBLC procedures to define the learning curve and threshold for p...

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Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease: Need for Procedural Standardization.

and up to 10% when D LCO is lower than 50% predicted) [3–5] . Furthermore, surgical lung biopsy is not worth performing in elderly subjects mainly due to the presence of comorbidities [6] . More recently, cryoprobes used through a flexible bronchoscope have been utilized to obtain lung tissue [7– 10] . The cryosurgical equipment operates by the JouleThomson effect, which dictates that a compres...

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Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease: Need for Procedural Standardization

and up to 10% when D LCO is lower than 50% predicted) [3–5] . Furthermore, surgical lung biopsy is not worth performing in elderly subjects mainly due to the presence of comorbidities [6] . More recently, cryoprobes used through a flexible bronchoscope have been utilized to obtain lung tissue [7– 10] . The cryosurgical equipment operates by the JouleThomson effect, which dictates that a compres...

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Bronchoscopic Cryobiopsy for the Diagnosis of Diffuse Parenchymal Lung Disease

BACKGROUND Although in some cases clinical and radiographic features may be sufficient to establish a diagnosis of diffuse parenchymal lung disease (DPLD), surgical lung biopsy is frequently required. Recently a new technique for bronchoscopic lung biopsy has been developed using flexible cryo-probes. In this study we describe our clinical experience using bronchoscopic cryobiopsy for diagnosis...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2019

ISSN: 0903-1936,1399-3003

DOI: 10.1183/13993003.00337-2019